Basic Information
VIS ID
TVIS10001017
Fusion event
HBV-chr20 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
62188377/63557024 (Hg38)
End
62188377/63557024 (Hg38)
Location type
Promoter;downstream
Target gene
FNDC11 ; HELZ2 ; SRMS
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-6793-3p
Nearest miRNA
hsa-mir-1-1/Upstream/270158; hsa-mir-1914/Downstream/362425;
Nearest TSS
ENST00000382410/Upstream/2881; ENST00000411579/Downstream/4581;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/481, chr20-CpG: 24/Downstream/763
Upstream sequence
CCCATCACCGTGACCGGGCTCCGGCCTTCCTTACCCACCTCCCTGGCTTGTGGGGCTCCCTCAGGGAATGACACTCCTAGGCCGTGATGCCTCCCACCAT
Downstream sequence
CCCCTGCCCAGCCTCGAGTGCTCATCAGCACGCCCGCCCGAGGAGGCAGCAGCACCACCGGGGATCCCTGGCTGTGAGCAGCTCAGCCGTGCCCCTCCAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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