Basic Information
VIS ID
TVIS10001046
Fusion event
HBV-LOC388572 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
176506/176506 (Hg38)
End
176506/176506 (Hg38)
Location type
Intronic
Target gene
LOC388572
Nearest miRNA
hsa-let-7a-2/Downstream/32830;
Nearest TSS
ENST00000527297/Upstream/36894; ENST00000342878/Downstream/16574;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/48729, chr11-CpG: 184/Downstream/30469
Nearby gene
LINC01001(-44586) ; SCGB1C1(+16574) ;
Upstream sequence
ccctaacccctaaccctaaccctaccctaacccaaccctaacccaaccctaactctagccctagccctagccctaagccctaagccctaagcctaacccc
Downstream sequence
aaccccaaccccaaccctaaccctaaccctaaccctTCCTCAGCCTCTCAACCTGCTTGGGTTATAGGTATGAGCCTGGGTGCCTGGCcaaacattccat
Target sequence
gcactcccaaatatcactttacagattctagaaaaacagtgttcccaaactgcttaatcaaaagaaaattttaactctgtgagatgaatgcacacac
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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