Basic Information
VIS ID
TVIS10001049
Fusion event
HBV-RBFOX3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
77254469/79258387 (Hg38)
End
77254469/79258387 (Hg38)
Location type
Intronic
Target gene
RBFOX3
Nearest miRNA
hsa-mir-10226/Upstream/1861333; hsa-mir-1250/Downstream/448789;
Nearest TSS
ENST00000595228/Upstream/22582; ENST00000592718/Downstream/49440;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/60200, chr17-CpG: 27/Downstream/205776
Upstream sequence
AGTGATACGCCGCAGACACAGAGAAAGGATCTGAAACGGATTCCCGCTTAAATCTCAAACCCTACTCAATACTCCTGTACTGAGGTGAAAGCAGAGGATA
Downstream sequence
ACATCTCCATTCCTCAGAACCCACCAGGTGTGTTGCCGTGGACCACAGTCAAGGTTGCTGCTGTTATGATTCAGCATTTACTGAGCACGGGAATGTGCTG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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