Basic Information
VIS ID
TVIS10001052
Fusion event
HBV-chr15 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
102521337/101981134 (Hg38)
End
102521337/101981134 (Hg38)
Location type
Promoter;downstream
Target gene
DDX11L9 ; MIR6859-1 ; MIR6859-2 ; WASH3P
miRNAs that regulate target gene
hsa-mir-93-3p ; hsa-mir-331-3p ; hsa-mir-149-5p ; hsa-mir-183-5p
Nearest miRNA
hsa-mir-10393/Upstream/7543;
Nearest TSS
ENST00000557528/Upstream/19726;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/18908, None/Downstream
Upstream sequence
ggttggggttagggttagggttagggttagggttagggttagggttagggttagggtagggttagggttagggttagggttagggttagggttagggtta
Downstream sequence
gggttagggttagggttagggttagggtttagggttagggttagggttagggttaNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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