Basic Information
VIS ID
TVIS10001054
Fusion event
HBV-chr15 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Reference genome
GRCh37/hg19
Start
102521392/102521392 (Hg38)
End
102521392/102521392 (Hg38)
Location type
Promoter;downstream
Target gene
DDX11L9 ; MIR6859-1 ; MIR6859-2 ; WASH3P
miRNAs that regulate target gene
hsa-mir-93-3p ; hsa-mir-331-3p ; hsa-mir-149-5p ; hsa-mir-183-5p
Nearest miRNA
hsa-mir-10393/Upstream/547801;
Nearest TSS
ENST00000557528/Upstream/559984;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/559166, None/Downstream
Upstream sequence
gtagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtttagggttagggttagggttagggtta
Downstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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