Basic Information
VIS ID
TVIS10001060
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
239931055/239009359 (Hg38)
End
239931055/239009359 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2J
Nearest miRNA
hsa-mir-10b/Upstream/1498371; hsa-mir-149/Downstream/59458;
Nearest TSS
ENST00000437798/Upstream/83090; ENST00000428471/Downstream/57622;
Nearest CpG islands
chr2-CpG: 20/Target, None/Upstream, None/Downstream
Nearby gene
LINC01940(-83090) ; HDAC4(+38809) ;
Upstream sequence
GCGCCCTGGAATTGGGATCTTCTCACGTGCCCTGTGGGTTTTGATCTCAGGTGTTCGTGGGCCTCCTCCCACGCTCCGTTTCGCTGGCCACGTGGGTGGA
Downstream sequence
CGGCTCCCTCTGACCTTCCTCACCTGACAATACCCAGGCGCTCCCTCCACCCCCTTCTATGCCCACCCGGCCAGATGGAACGTTCTTTTTTTCCCACCTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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