Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001069
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
Start
End
1352708/1417328 (Hg38)
Location type
Promoter;downstream
Fragile sites / regions
miRNAs that regulate target gene
hsa-mir-4758-3p ; hsa-mir-4641 ; hsa-mir-298 ; hsa-mir-922 ; hsa-mir-4747-3p ; hsa-mir-4323 ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6826-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-6729-3p ; hsa-mir-449b-3p ; hsa-mir-3157-5p ; hsa-mir-4514 ; hsa-mir-4691-3p ; hsa-mir-4692
Nearest miRNA
hsa-mir-12136/Upstream/77620; hsa-mir-101-1/Downstream/1710647;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/9773, chr1-CpG: 113/Downstream/2451
Upstream sequence
gacaagaatttaccgtataacatgcttttcacataaattcagcctcccctttttttttcttttttaaagcgaactttttttatgtctttggactagactg
Downstream sequence
tctgaggccacaagattaaaagttaccattaacatgttacactgttaacttttagcaaacttcgcttttgttgaaaaccttggaagtttgggatttcaat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.