Basic Information
VIS ID
TVIS10001085
Fusion event
HBV-chr10 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
132816/86876 (Hg38)
End
132816/86876 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-107/Downstream/554813;
Nearest TSS
ENST00000562162/Upstream/12713; ENST00000439456/Downstream/47589;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/10196, chr10-CpG: 259/Downstream/47766
Nearby gene
TUBB8(-37638) ; ZMYND11(+47589) ;
Nearest cancer related gene
ZMYND11(TSG, +47589) ;
Upstream sequence
ttcttttttttttttttttttttagacagagtctccctctgttgcccaggctggagtgcagtagtgtgatcttggttaactgcaacctccaactcctggg
Downstream sequence
ttcaagcgattctcctgcctcagcctcctgagtagttgggattataggctcctgctgccacagccagctaatttttttgtatttttagtagagatagcat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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