Basic Information
VIS ID
TVIS10001124
Fusion event
HBV-ENPP7P8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q13.4
Reference genome
GRCh37/hg19
Start
71453369/71742323 (Hg38)
End
71453369/71742323 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
ENPP7P8
Nearest miRNA
hsa-mir-10392/Upstream/268755; hsa-let-7a-2/Downstream/329905;
Nearest TSS
ENST00000527297/Upstream/36919; ENST00000526393/Downstream/45187;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/102371, chr11-CpG: 121/Downstream/44202
Nearby gene
KRTAP5-11(-159448) ; FAM86C1(+45188) ;
Upstream sequence
ttaagacccaaaacggggacagaaatgcccctgagagagcagcggtatactgggatagatgaggatggtcacgtggtggggaggcgtgtttttgggtacc
Downstream sequence
ggcccttcacctctgcccactttctcaactggaaaagcaataccccgtcctgtaccgaaaagccacaagctctgattgatttgctccaaactattatcca
Target sequence
ACATTGTTTTTTTCATTCTCTCAGAGTCTCCCCTCATACTTCCTTTCCTGTTCCCCCAAAACAGAGACCAAAAAGATTAGGTGGGCCTGATTTAAACTACCCCAGAATAACACCAGCTTTCACC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate