ACTA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001128
Fusion event
HBV-ACTA2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q23.31
Reference genome
GRCh37/hg19
Start
90700309/88940552 (Hg38)
End
90700309/88940552 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
ACTA2
miRNAs that regulate target gene
hsa-mir-484
Nearest miRNA
hsa-mir-1265/Upstream/1436598; hsa-mir-107/Downstream/122783;
Nearest TSS
ENST00000439456/Upstream/1055; ENST00000460510/Downstream/12195;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/59686, chr10-CpG: 68/Downstream/49984
Upstream sequence
TGGCAGGGTTCAAGTCTCAAGCCTCAAATTTGGAGCATAAAATAAGCCTCAGGCATGTTCAGAAACCTAAATGTTTGGACAATACCAAATTGCTAAGGGG
Downstream sequence
AGGACAGGTAGCTGGAGCCACCAGCACTGAGGACATACAATGTTTCTGGCAATGCTGACACTTTCCTCTTGTGAAGGGAGGACTGGGTGCACCGGCTTAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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