Basic Information
VIS ID
TVIS10001129
Fusion event
HBV-chr10 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q23.31
Reference genome
GRCh37/hg19
Start
92044697/90284940 (Hg38)
End
92044697/90284940 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-107/Upstream/692113; hsa-mir-1287/Downstream/5779375;
Nearest TSS
ENST00000439456/Upstream/327567; ENST00000453889/Downstream/169230;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/446905, chr10-CpG: 137/Downstream/572123
Nearby gene
LINC00865(-444079) ; HTR7(+455879) ;
Upstream sequence
TGATTTTTAATTTTTCTGTTCATGTGAATACTTTTTAAAAATTCATTTTTAAGTTAAAACTTACTTGCTATTCCTGTGGGTCAGAACACCTTCAGCCTTC
Downstream sequence
CTGACAGAAAGCAAGAGCTTTCTCTTACACCAAGAAGTCACTGGTAATGTATGTGTACATCTCAGGGGCCCTTTTTTCTGAGGAGATTCAGCCTTAAATT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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