Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001181
Fusion event
HBV-RAPGEF6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
End
130803730/131468037 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-940 ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6881-3p ; hsa-mir-188-3p ; hsa-mir-4268 ; hsa-mir-130b-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-766-3p ; hsa-mir-877-3p ; hsa-mir-4267 ; hsa-mir-6736-3p ; hsa-mir-4698 ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-10397/Upstream/2070890; hsa-mir-103a-1/Downstream/749812;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/203324, chr5-CpG: 85/Downstream/166685
Upstream sequence
ATACACTGAGACAGAGGGACGTCATGAATAAGAGGTCACCGAGATCTTGAGTCAGTCATTCAGTTACTTAACAAAGAGTTTTCTAAAACTAGCAATGTAC
Downstream sequence
aaTCTTGGggtcgggcgcagtggcttatgccagtaattccagcactttgggaggccgaggtgggcggatcacgaggtcaggagaatgagaccatcctggc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.