Basic Information
VIS ID
TVIS10001192
Fusion event
HBV-CCDC178 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
30534718/32954754 (Hg38)
End
30534718/32954754 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA18A
Target gene
CCDC178
Nearest miRNA
hsa-mir-1-2/Upstream/2655794; hsa-mir-122/Downstream/2636983;
Nearest TSS
ENST00000575820/Upstream/679; ENST00000647014/Downstream/181323;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/182415, chr18-CpG: 45/Downstream/485792
Upstream sequence
GAGAGAATTGGGAGGTAGTGATGGAAATGACTTCAAAGGAACAGAAAGCAGTATCAGACAGTCCCCAGGAGCAAAAGAGATATCTGTCTCCTTTCACATT
Downstream sequence
TTATCTCTTTCCCCAAACTCAGTAGTGTTAACAATTTTTGTTTAATAAAAAAGGAGGGAAGAAAAGAATGAATGGTGTAAGACAGTGTTTTGTTGAATTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate