MBTD1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001203
Fusion event
HBV-MBTD1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
49309557/51232196 (Hg38)
End
49309557/51232196 (Hg38)
Location type
Intronic
Target gene
MBTD1
miRNAs that regulate target gene
hsa-mir-151a-3p ; hsa-mir-128-3p ; hsa-mir-101-3p ; hsa-mir-27a-3p ; hsa-mir-149-5p ; hsa-mir-1277-5p ; hsa-mir-7856-5p ; hsa-mir-6083 ; hsa-mir-3658 ; hsa-mir-190a-3p ; hsa-mir-3688-3p ; hsa-mir-8076 ; hsa-mir-5011-5p ; hsa-mir-590-3p ; hsa-mir-5587-5p ; hsa-mir-676-5p ; hsa-mir-6507-3p
Nearest miRNA
hsa-mir-10226/Upstream/463466; hsa-mir-1250/Downstream/5659074;
Nearest TSS
ENST00000595228/Upstream/6972; ENST00000583725/Downstream/24633;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/64910, chr17-CpG: 150/Downstream/27545
Upstream sequence
ctctcggtgaagaggcttctctgggattttgtaatcacaggcctgacctcatgagttaagtctgaggttgaaattttctcttccctctatggtcagggaa
Downstream sequence
ctcccaggccaagaaattaaagtggttccaggctaccagtgccctttgatacctagcagaagcaaacctaaattagatcaggaaataagtcacctaccat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate