Basic Information
VIS ID
TVIS10001214
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
3171991/3132357 (Hg38)
End
3171991/3132357 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA7B
Nearest miRNA
hsa-mir-339/Upstream/605212; hsa-mir-10399/Downstream/1656208;
Nearest TSS
ENST00000635602/Upstream/45936; ENST00000478527/Downstream/25898;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/88510, chr7-CpG: 185/Downstream/168365
Nearby gene
CARD11(-88412) ; SDK1(+169089) ;
Nearest cancer related gene
CARD11(OG, -88412) ;
Upstream sequence
TCTATTTTTATTTTCTGAAGGAGTACAGCGTGTATATATTAAACACAGCTAAATGAACCGAGAAAGAAATCCAGATGTTTAACCATGAAATCTAAATTTT
Downstream sequence
gggacagaactttgctctatccccaggctggagtacaatggtgtgatctcggcacactgcaacttccgcctcccaggttcaagtgattctcctgcctcag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate