PHKB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001235
Fusion event
HBV-PHKB integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
47539144/47505233 (Hg38)
End
47539144/47505233 (Hg38)
Location type
Intronic
Target gene
PHKB
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-484 ; hsa-mir-6882-3p ; hsa-mir-4312 ; hsa-mir-100-3p ; hsa-mir-4258 ; hsa-mir-1265
Nearest miRNA
hsa-mir-1225/Upstream/13341560; hsa-mir-11401/Downstream/2787383;
Nearest TSS
ENST00000527434/Upstream/5477; ENST00000566436/Downstream/88917;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/43937, chr16-CpG: 31/Downstream/739188
Upstream sequence
agtgaatgattggaggttttacgacccaaaggatctccacctactctcacactttagttgggtaagaagcccggcttgctggcgtgtggagccgggtatg
Downstream sequence
gaatgtgagtgcctagtgggccgcttctggtaagcagacctggctctgcgggatgaaccgaatgccggattaaggtgcccaatgcccacacactcatcag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate