Basic Information
VIS ID
TVIS10001241
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
66601080/67305252 (Hg38)
End
66601080/67305252 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/7601549; hsa-mir-103a-1/Downstream/4864215;
Nearest TSS
ENST00000502646/Upstream/37230; ENST00000503106/Downstream/74126;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/141485, chr5-CpG: 159/Downstream/909792
Nearby gene
CD180(-108463) ; LINC02219(+884624) ;
Upstream sequence
CAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAgggcggggccgcggaaaggaaggggaggggctgggagggcccggagggggctgggccg
Downstream sequence
ttAGGATGATGTAAGTCAAAAATCAACTCCCATTGAGGTTAAAAAAAGTACTGGCTGCGTAGCCCTGTTGCTGTCAAAGGAGCCCTCATTTTCTCAAGCC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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