Basic Information
VIS ID
TVIS10001251
Fusion event
HBV-MTERF3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
97262923/96250695 (Hg38)
End
97262923/96250695 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
MTERF3
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-12123/Upstream/1177699; hsa-mir-10400/Downstream/2142950;
Nearest TSS
ENST00000518652/Upstream/15061; ENST00000517557/Downstream/6375;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/89043, chr8-CpG: 111/Downstream/10692
Upstream sequence
tcctcaaagagatagaaaaatccctgcctccaggcttttgcgccagctgtttccttgcctgagatgctcttccccaagatacctgcagctccctcacgcc
Downstream sequence
ggggggagggggagggggagaagaagaaTGGGTACTTGAATGAAAGAACTGTTGTAAATACTTAATTTAGATCAAAGAAGGTCTATAACAAAAAAAATTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate