VPS72 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001261
Fusion event
HBV-VPS72 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
151157117/151184641 (Hg38)
End
151157117/151184641 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
VPS72
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-2053 ; hsa-mir-6857-5p ; hsa-mir-2110 ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-491-5p ; hsa-mir-92a-2-5p ; hsa-mir-4450 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-4751 ; hsa-mir-6716-5p ; hsa-mir-4438
Nearest miRNA
hsa-mir-101-1/Upstream/632627; hsa-mir-1182/Downstream/361155;
Nearest TSS
ENST00000473358/Upstream/8357; ENST00000424999/Downstream/5502;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/37744, chr1-CpG: 52/Downstream/13730
Upstream sequence
TTTTATTTATTTATTTTGAAATGTTGTACTTGGAAATAAtttttttttctttttttttttttgagatggaatctcgctctgtcgcccaggctggagtaca
Downstream sequence
gtggcacgatctcggctcactccaacctctgcttcctgggttcaaacaattctcctgcctcagactcccgagtagctgggagtacaggtgcatgccacca
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate