hsa-mir-3159 _LIHC.png
NSMCE2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001273
Fusion event
HBV-NSMCE2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
126370531/125358289 (Hg38)
End
126370531/125358289 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
NSMCE2
miRNAs that regulate target gene
hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-764 ; hsa-mir-6504-3p ; hsa-mir-3159 ; hsa-mir-552-3p ; hsa-mir-1303 ; hsa-mir-3188 ; hsa-mir-6866-5p ; hsa-mir-877-5p
Nearest miRNA
hsa-mir-12123/Upstream/536231; hsa-mir-10400/Downstream/2437673;
Nearest TSS
ENST00000518652/Upstream/6873; ENST00000521460/Downstream/4737;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/266409, chr8-CpG: 216/Downstream/70940
Upstream sequence
acctactgatatgtgatgtcacccccggaggcccagctgtaaaattcctctctttgcactctttctctttatttctcagactggctgacacttagggaaa
Downstream sequence
gccactgcattccaacctgggcaacagagctagactctgtctcaaaaaaaaaaaaaGGTTTAGGTAAATTCATGGCTAACTCATGAATGATAAATTATTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate