VISDB Viral Integration Site DataBase

VIS ID

TVIS10001287

Fusion event

HBV-ARHGAP42 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr11

Cytoband

q22.1

Reference genome

Start

End

100735607/100864876 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-221-3p ; hsa-mir-28-5p ; hsa-mir-222-3p ; hsa-mir-138-5p ; hsa-mir-376c-3p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-4299 ; hsa-mir-3692-5p ; hsa-mir-4633-3p ; hsa-mir-6071 ; hsa-mir-6500-5p ; hsa-mir-587 ; hsa-mir-6131 ; hsa-mir-3185 ; hsa-mir-133a-5p ; hsa-mir-93-3p ; hsa-mir-885-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-4511

Nearest miRNA

hsa-mir-10392/Upstream/4523350; hsa-let-7a-2/Downstream/654944;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/177206, chr11-CpG: 170/Downstream/262423

Upstream sequence

AAATATCTTCGTTATCAAAATGTTTCAAATATGCCCAAACTTACCCCTTGAACCAAGCATAGTTAATACGTTTCCCTTATTTTTGAAATACCCCTTGATG

Downstream sequence

TCCAGGGTCCCCAGTACACAGTAGGCACTTAATGGTAACTTGTTTCATTAGAGATAACAGACTTGGGAAATACTGCCCATAAAAGTTAAATTTTTATTTC

Target sequence

GAATCACAGGGTTGCAGCAGGGTTCATGAGGGTCAAGGGGCCAGCATGGGGGACTTCCGCAAGAGAGCCCCTGGCCCCCCTCAGCCTGCCTGCCCTATTGCCTCAGGGGCAGAGACCCTCCTGGGAAGATAGACTGCTGCCTGCACATTTTGCTGACAGATAACTTTCCCGCTGGTGTAATTAGGATTCAGAGTATCTGGCCCACCCCTGGCCTGATCCTCCCTCCCAAGGGCCAATCACAGACCCTGCTGGAGG