VISDB Viral Integration Site DataBase

VIS ID

TVIS10001307

Fusion event

HBV-GRIN2A integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr16

Cytoband

p13.2

Reference genome

Start

End

9915769/9821912 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-3915 ; hsa-mir-4710 ; hsa-mir-657 ; hsa-mir-3679-5p ; hsa-mir-3665 ; hsa-mir-1185-5p ; hsa-mir-3928-3p ; hsa-mir-125a-3p ; hsa-mir-583 ; hsa-mir-192-3p ; hsa-mir-6806-5p ; hsa-mir-5189-3p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-5589-3p ; hsa-mir-216a-5p ; hsa-mir-216b-5p ; hsa-mir-4753-3p ; hsa-mir-130b-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6840-3p ; hsa-mir-873-5p ; hsa-mir-1228-3p ; hsa-mir-3914 ; hsa-mir-6800-3p ; hsa-mir-1276 ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-3941 ; hsa-mir-2355-5p ; hsa-mir-136-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-8485 ; hsa-mir-329-3p ; hsa-mir-148a-5p ; hsa-mir-3123 ; hsa-mir-3154 ; hsa-mir-3925-5p ; hsa-mir-411-5p ; hsa-mir-5010-3p ; hsa-mir-6770-5p ; hsa-mir-6832-5p ; hsa-mir-7515

Nearest miRNA

hsa-mir-1225/Upstream/4189346; hsa-mir-11401/Downstream/1484528;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/729080, chr16-CpG: 282/Downstream/358174

Nearest cancer related gene

GRIN2A(TSG, No orient, 0)

Upstream sequence

TCTTTTCTTTCTCTTTCATCAATGTTATACAATTAGTTTTTTCATAAAGCTCCTACTAGCAAGCTACTCCTCCCCACACTCAGAAAACCTCCTACCTAAA

Downstream sequence

ATCTGATAAAAATCTTTGTTTTCACTACTTTAAACTCTTGGCCTTCTTGGATCTTTCTATTTGTTAAAATATCCTATGGAGTTGGACAAACTTCTTTATC