Basic Information
VIS ID
TVIS10001321
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64426114/63560396 (Hg38)
End
64426114/63560396 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/2637712; hsa-mir-1243/Downstream/2716428;
Nearest TSS
ENST00000502981/Upstream/66118; ENST00000509473/Downstream/721140;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/210530, chr4-CpG: 32/Downstream/2109079
Nearby gene
LPHN3(-1487946) ; TECRL(+718063) ;
Upstream sequence
tgggcgacagagcgagactccgtctcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaga
Downstream sequence
TTATTTTAGATTCTTGTTGAACACTGAGATAAAATATTCAGGGGAATATTCAGAAAAATAGAATGCTAGTTTTTTTTTTATGTTTTGAAGTATCTTGAAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate