Basic Information
VIS ID
TVIS10001324
Fusion event
HBV-LOC107987070 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
70348315/65817728 (Hg38)
End
70348315/65817728 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA9F
Target gene
LOC107987070
Nearest miRNA
hsa-mir-101-2/Upstream/24583893; hsa-let-7a-1/Downstream/4992247;
Nearest TSS
ENST00000422679/Upstream/46773; ENST00000619435/Downstream/203088;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/54101, chr9-CpG: 32/Downstream/209783
Nearby gene
FOXD4L5(-169500) ; FOXD4L4(+78308) ;
Upstream sequence
CTGTAAGGAGAGTTACATAAGTGACGGGGGCAGGAGTGGCAATACCAGGACAGTGTACAGGCCCCCCAGGGACTCTGGGAAAGGGTCACTAATCATCTGG
Downstream sequence
cctgcattgccctgccctcctctgccctgGTGCTACCATGGCGCTGCTTGGgccctagctctgcctcgactctggacctgccctgactctgctcagccct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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