VISDB Viral Integration Site DataBase

VIS ID

TVIS10001337

Fusion event

HBV-chr4 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr4

Cytoband

q31.21

Reference genome

Start

End

144434173/143513020 (Hg38)

Location type

Promoter;downstream

Target gene

SMARCA5 ; SMARCA5-AS1

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-424-5p ; hsa-mir-99a-5p ; hsa-mir-100-5p ; hsa-let-7a-2-3p ; hsa-mir-101-3p ; hsa-let-7g-3p ; hsa-mir-99b-5p ; hsa-mir-3667-5p ; hsa-mir-606 ; hsa-mir-3133 ; hsa-mir-4511 ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-186-5p ; hsa-mir-8070 ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-7703 ; hsa-mir-500a-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-542-3p ; hsa-mir-661 ; hsa-mir-767-5p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-4679 ; hsa-mir-6776-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6742-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-let-7c-3p ; hsa-mir-493-5p ; hsa-mir-144-3p ; hsa-mir-151a-5p

Nearest miRNA

hsa-mir-12113/Upstream/169485; hsa-mir-1305/Downstream/2895563;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/175086, chr4-CpG: 107/Downstream/76

Upstream sequence

GATGTAGAAAAGAGCTTTTTAGTAAATTATTAGATGTTCTCATTCAAATTGAAACTTTGTGTAGAGAAATACATTTATGTATCTATACCAATGCAAGTAC

Downstream sequence

aaaaaaTCACACTAACGGACTTTTTTTTTTTTTCTAACAACAAAAAACCGTGAGACTTCACTTGGGGTAACCATAACGTCGTCAAGGCTGTGGCGTCACG