Basic Information
VIS ID
TVIS10001343
Fusion event
HBV-MTND5P19 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q42.3
Reference genome
GRCh37/hg19
Start
235702518/235539218 (Hg38)
End
235702518/235539218 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
MTND5P19
Nearest miRNA
hsa-mir-101-1/Upstream/349102; hsa-mir-1537/Downstream/313782;
Nearest TSS
ENST00000473358/Upstream/34737; ENST00000412098/Downstream/49741;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/33899, chr1-CpG: 35/Downstream/102800
Nearby gene
B3GALNT2(-34737) ; GNG4(+8467) ;
Upstream sequence
GACTGGGGCTGGGCCTTCTATGGCAGATGGGAGTCAGGGATGGAGGCCGAATTGAGCTGACTTTCCTGCTGCTGCTAAGAGAAGGCTAATTAATGGGAGG
Downstream sequence
GAGTTGGGGGTAGGGTCTAGAATTTATTTTTTGCTGATATTCTCATGTGTTGGAGGACAGGAGGAATCATGCTATAGCTGAAATAAAGCCAATATTGCCG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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