Basic Information
VIS ID
TVIS10001344
Fusion event
HBV-chr18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
p11.32
Reference genome
GRCh37/hg19
Start
587739/587739 (Hg38)
End
587739/587739 (Hg38)
Location type
Promoter;downstream
Target gene
CETN1 ; CLUL1
miRNAs that regulate target gene
hsa-mir-128-3p
Nearest miRNA
hsa-mir-8078/Upstream/475400; hsa-mir-1-2/Downstream/3297614;
Nearest TSS
ENST00000575820/Upstream/7382; ENST00000579443/Downstream/9249;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/6840, chr18-CpG: 39/Downstream/9090
Upstream sequence
agtgaaggtgtttggactattaccttgagtatgtatcgtttctatgtgttgggagcttttcaagtcctctcttgtaacaattttgaaatatacaatgcct
Downstream sequence
tgttgttaactagtcaccctgctctgctctcaaacactaggatttattccttctgtctaactgggtgtttgtacccattaaccaacctgtcttcatcccc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate