Basic Information
VIS ID
TVIS10001359
Fusion event
HBV-LOC105372675 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
52804485/54187946 (Hg38)
End
52804485/54187946 (Hg38)
Location type
Intronic
Target gene
LOC105372675
Nearest miRNA
hsa-mir-103a-2/Upstream/119461; hsa-mir-1-1/Downstream/3133556;
Nearest TSS
ENST00000382410/Upstream/13973; ENST00000474326/Downstream/19901;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/13499, chr20-CpG: 70/Downstream/19845
Nearby gene
CYP24A1(-13969) ; PFDN4(+20017) ;
Upstream sequence
TTAGTTCTGCTTCTAGTGGAAATGGGGAATTCATATATAATAGTATTTCTAATGTTTAGGTTTAATTTTTTAAAGTTGTGAATTTCCAAGCTCTCACCAT
Downstream sequence
CTCCTTAGATCTTCACAAGTCATGACATATATACCAGGTTGACCACCATTTTACAAATAAGAAAATTCTGAGAGCAGAGAATTTAAATCCTGTCTTTATT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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