Basic Information
VIS ID
TVIS10001465
Fusion event
HBV-chr18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
18519140/20939179 (Hg38)
End
18519140/20939179 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-3156-2/Upstream/6108937; hsa-mir-1-2/Downstream/744339;
Nearest TSS
ENST00000575820/Upstream/5774712; ENST00000579454/Downstream/15691;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/5608004, chr18-CpG: 113/Downstream/171800
Nearby gene
ROCK1(+10563) ;
Nearest cancer related gene
ROCK1(OG, +10563) ;
Upstream sequence
ttatatgaatgcgcgctttcaacgaaatcctcaaagcaatccaaatatccacttgcagattccacaaaaagagtgtttcaaaactcctctatcaatagaa
Downstream sequence
agtttcaactctgttagttgaggacacacatcacaaataagtttctaagaatgcttctgtgtagattttacatgaagatattcccgtttccaatgccatc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate