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VISDB
Viral Integration Site DataBase
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TVIS10001470
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001470
Fusion event
HBV-KMT2B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
36212579/35721677 (Hg38)
End
36212579/35721677 (Hg38)
Location type
Exonic
Fragile sites / regions
FRA19A
Target gene
KMT2B
miRNAs that regulate target gene
hsa-mir-7515
;
hsa-mir-302a-5p
;
hsa-mir-3154
;
hsa-mir-6782-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-5692a
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-93-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-20b-5p
;
hsa-mir-153-3p
;
hsa-mir-1224-3p
;
hsa-mir-1294
;
hsa-mir-1914-3p
;
hsa-mir-214-3p
;
hsa-mir-31-5p
;
hsa-mir-3184-5p
;
hsa-mir-3619-5p
;
hsa-mir-3689d
;
hsa-mir-423-5p
;
hsa-mir-4316
;
hsa-mir-4426
;
hsa-mir-4440
;
hsa-mir-4459
;
hsa-mir-4647
;
hsa-mir-4662b
;
hsa-mir-4688
;
hsa-mir-4722-5p
;
hsa-mir-5194
;
hsa-mir-6085
;
hsa-mir-6165
;
hsa-mir-6734-5p
;
hsa-mir-6738-5p
;
hsa-mir-6743-5p
;
hsa-mir-6789-5p
;
hsa-mir-6813-5p
;
hsa-mir-6851-5p
;
hsa-mir-761
;
hsa-mir-7704
;
hsa-mir-885-3p
Nearest miRNA
hsa-mir-10395/Upstream/376050; hsa-let-7e/Downstream/3687946;
Nearest TSS
ENST00000633603/Upstream/775;
ENST00000592092/Downstream/11581;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/1653
,
chr19-CpG: 24/Downstream/2049
Upstream sequence
TGCAAACCCAGCTCCTGCCCCAGGCACTACCGCCACCACAGCCACAGCTGCAGCCACCGCCGTCACCACAGCAGATGCCTCCCCTGGAAAAAGCCCGGAT
Downstream sequence
TGCGGGCGTGGGTTCCTTGCCGCTGTCTGGGGTAGAGGAGAAGATGTTCAGCCTCCTCAAGAGAGCCAAAGTGCAGCTATTCAAGATCGATCAGCAGCAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Sample Information
×
Sample name
077045T
Sample type
Tumor
Gender
Female
CpG Island Information
×
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