Basic Information
VIS ID
TVIS10001478
Fusion event
HBV-chr3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
135023399/135304557 (Hg38)
End
135023399/135304557 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/866651; hsa-mir-1224/Downstream/16261319;
Nearest TSS
ENST00000440867/Upstream/171765; ENST00000447251/Downstream/661116;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/507419, chr3-CpG: 47/Downstream/661507
Nearby gene
EPHB1(-44092) ; PPP2R3A(+661116) ;
Upstream sequence
CATGAAAATAAAGCATACAAGTGTGTAACATTTTTGCGTACCAAATAGCTTCCAAATAGAAAATATAATGGACACaagtatcttgcccaaggtcatacaa
Downstream sequence
GTTGGCCAGGATCCAAAGATTGACCAGTCCTAAGGCCCTAGGGAAAAGTACGTGTCCAAGCATTAGGCAACTGAAGATTGACCAAGCAGGGTAGCAAGAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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