Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001483
Fusion event
HBV-C15orf41 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
Start
End
37020299/36728098 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-17-5p ; hsa-mir-574-5p ; hsa-mir-340-5p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-3713 ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-4742-5p ; hsa-mir-5586-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-595 ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609
Nearest miRNA
hsa-mir-1233-1/Upstream/801175; hsa-mir-10393/Downstream/244723;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/148402, chr15-CpG: 36/Downstream/90062
Upstream sequence
GCATGCTAAGAATTACTGTATGGCTTTGGTGTCTCCATGATTTTGAGAGGAAGATGATCCTACCAAAAGGAAAAACAAAGCTCCCAAGTATTCTTATGAT
Downstream sequence
ACACAGGTAGTTCTTTCCCCTCATATGGCTTTGTATGTGGAGGGAGGAATTGTTTTTGTTTTTTTGTTTTTTGTCATGCATCACTCTATTAAAAGCTTAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.