Basic Information
VIS ID
TVIS10001484
Fusion event
HBV-chr18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
51063558/53537188 (Hg38)
End
51063558/53537188 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/299998; hsa-mir-122/Downstream/1942033;
Nearest TSS
ENST00000575820/Upstream/6891; ENST00000579506/Downstream/31095;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1194836, chr18-CpG: 59/Downstream/687211
Nearby gene
DCC(-1285) ; MBD2(+614413) ;
Nearest cancer related gene
DCC(TSG, -1285) ;
Upstream sequence
cttggattgcctcccttccctttttatcttgcccccttcccctaatggtttctcctgggagcacttcacagtaaatcactttcatgcaaatctttatggc
Downstream sequence
aaggtctgtttctagggaattcactcaaggcaAGATCCTTCTAGCTGTGATCCAATTTCAACACACAAACAACAAATGAATAAAATACTCTTTTCATCAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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