SORCS3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001487
Fusion event
HBV-SORCS3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
106508859/104749101 (Hg38)
End
106508859/104749101 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
SORCS3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-107/Upstream/480696; hsa-mir-202/Downstream/6148989;
Nearest TSS
ENST00000439456/Upstream/82901; ENST00000393176/Downstream/409827;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/106047, chr10-CpG: 100/Downstream/2414921
Upstream sequence
GCAGAGTCCTGAAGCAGGAGCATGGCTATGAGAAGGTCACCACTCCATGGGGGGCAGGCAATTCCAAGGGAAGGGGCTTTTGGGTAACCTGCTTCATGTC
Downstream sequence
TACTGCAGTTAATTTTTGTGTAGCATGGAGAGTTGTGATTTTACTTCTTGTTTTCCAACTCTGAGGATTAATCAAGTGTGGTTACTGAGCAGTGACCATG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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