Basic Information
VIS ID
TVIS10001493
Fusion event
HBV-GSAP integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
76943592/77314275 (Hg38)
End
76943592/77314275 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
GSAP
Nearest miRNA
hsa-mir-10525/Upstream/1399006; hsa-mir-10399/Downstream/14889740;
Nearest TSS
ENST00000635602/Upstream/21222; ENST00000608884/Downstream/540;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/192198, chr7-CpG: 111/Downstream/101248
Upstream sequence
caagctctgcctcccgggttcacgccattctcctgcctcagcctcccaagtagctgggactacaggcgcccaccaccatgcccggctaatttttttgtat
Downstream sequence
gctcttggtgactgcacaggttgcacacccaagaagctagccttgGTGGTGCTCAGGCTGGAACTAGCACTCTGGCAAACTCAGGGCTTCTTACCTTTCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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