ROR1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001497
Fusion event
HBV-ROR1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
64597273/64131590 (Hg38)
End
64597273/64131590 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
ROR1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-19b-3p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-3190-5p ; hsa-mir-27b-3p
Nearest miRNA
hsa-mir-12132/Upstream/804606; hsa-mir-101-1/Downstream/448257;
Nearest TSS
ENST00000473358/Upstream/19385; ENST00000646967/Downstream/39707;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/356482, chr1-CpG: 121/Downstream/338281
Upstream sequence
TTTGCAACCATTGGCCCTCTCCCAAGGTCCCTCTACCTTGGCCCTTGTGTAAATGATATTTtttttttaattaaggtggaattcacataacatagagttc
Downstream sequence
accattttaTTTTATTATTTATTTTGTTATCGTTATGttttaaagagatggtcttgctctgtcacccaggctggagtgcagtgatgtgatcatggctaac
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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