YEATS4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001504
Fusion event
HBV-YEATS4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37/hg19
Start
69774315/69380535 (Hg38)
End
69774315/69380535 (Hg38)
Location type
Intronic
Target gene
YEATS4
miRNAs that regulate target gene
hsa-mir-6514-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-8084
Nearest miRNA
hsa-let-7i/Upstream/107317; hsa-mir-1178/Downstream/204187;
Nearest TSS
ENST00000382841/Upstream/20756; ENST00000549261/Downstream/68935;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/20227, chr12-CpG: 46/Downstream/89679
Nearest cancer related gene
YEATS4(OG, No orient, 0)
Upstream sequence
ttactttctcccaaacaaacggagtttctgtttctgtgctgaactgcctagacctgaggagggatgacacaagcacccctttagccaccaccactgggac
Downstream sequence
tgccttaggtcagacttgaagccagcacattactgggtcttgcccaaggcccactgtaaccgctgcctggctgccacctatgtttgtgtgaggccctaag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate