Basic Information
VIS ID
TVIS10001506
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
155961132/156168438 (Hg38)
End
155961132/156168438 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/4734799; hsa-mir-153-2/Downstream/1405898;
Nearest TSS
ENST00000635602/Upstream/205806; ENST00000625073/Downstream/267395;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/12478, chr7-CpG: 15/Downstream/150103
Nearby gene
SHH(-356165) ;
Upstream sequence
TGTCAGCATAGTCCACTCACCCCGATTTCCATGTATGCATATGTGCACACTCCATGTCCCGTTTTTAATCCCTTTCTCTTCCTGCCCACCCCAACCCAGC
Downstream sequence
CACCACCGGCAATGCATAGCCTTCCTCCAGCCCGGGGAGCCCGCGGCCCCTTCCCATCTCACCGTCCACTCCACTCCAATACTTTTCTGGAAGAGTCTTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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