EXOC6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001551
Fusion event
HBV-EXOC6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
GRCh37/hg19
Start
94750724/92990967 (Hg38)
End
94750724/92990967 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
EXOC6
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-31-5p ; hsa-mir-4668-3p ; hsa-mir-6739-3p ; hsa-mir-6853-3p ; hsa-mir-1206
Nearest miRNA
hsa-mir-107/Upstream/3398140; hsa-mir-1287/Downstream/3073348;
Nearest TSS
ENST00000439456/Upstream/62593; ENST00000458552/Downstream/6507;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/141685, chr10-CpG: 255/Downstream/69302
Upstream sequence
aaatgtgtgcctcagcaaatgaagttctgcttgtactagactctgagagtcaatatcaagaattgaaacctaaatacaaattcatgagtgacaaagacct
Downstream sequence
actTTGTGCTATCTTTTTGTGTATGGCTGTTTATAATAGTCTGCCACCTACATCTATGAAAGGGAAGCCAGTTTGCTTGAGTGACATTTGTCAACTTTAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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