ATP11B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001559
Fusion event
HBV-ATP11B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q26.33
Reference genome
GRCh37/hg19
Start
182581698/182863910 (Hg38)
End
182581698/182863910 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
ATP11B
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-652-3p ; hsa-mir-222-3p
Nearest miRNA
hsa-let-7g/Upstream/6348759; hsa-mir-1224/Downstream/1022890;
Nearest TSS
ENST00000440867/Upstream/26793; ENST00000482070/Downstream/1617;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/69416, chr3-CpG: 91/Downstream/116051
Upstream sequence
CGCTGCTGTCTCTGGGCCTTGTGCCACAGCTGAATGCTACAGAGTGAGATGGCTGCCTTCTCTTTGAAGCATTTACGTCCCTGTCAAATACCTTTTTGCC
Downstream sequence
CTTTTTTTAATTAACTTGCATGGGGTCTTTAAATTCCAGTTCAACATTGCTATAAATACTGGGCAACATTTAATATCAAATAGTAAAGATAAAGTATTCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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