THSD7B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001589
Fusion event
HBV-THSD7B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
137674999/136917429 (Hg38)
End
137674999/136917429 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
THSD7B
Nearest miRNA
hsa-mir-128-1/Upstream/1251951; hsa-mir-10b/Downstream/3669197;
Nearest TSS
ENST00000437798/Upstream/35250; ENST00000485379/Downstream/73463;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/151303, chr2-CpG: 71/Downstream/1584034
Nearby gene
CXCR4(-799274) ; THSD7B(+73463) ;
Upstream sequence
TATTTAGCTTACAAAATAGCAGATTTTATTGGGTTGTTTTAGCAGGAATGGATGGGGCTGATCGTTGCATGGTTTAGTCTGCGGACTCACAAAGCCAGCT
Downstream sequence
CTTGTCTAATTGAGTCAGTGAGTCAGCTTATGTGTATTGAGCTCTCAGCTGGGGGTGGGGTGGAACTTTTAACCAGAATTGAGCATCTGCTCAGTGCTTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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