MRPL1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001595
Fusion event
HBV-MRPL1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
78776129/77854975 (Hg38)
End
78776129/77854975 (Hg38)
Location type
Promoter
Target gene
MRPL1
miRNAs that regulate target gene
hsa-mir-16-5p
Nearest miRNA
hsa-mir-12113/Upstream/1279349; hsa-mir-1243/Downstream/4898362;
Nearest TSS
ENST00000502981/Upstream/35360; ENST00000515625/Downstream/7545;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/34574, chr4-CpG: 20/Downstream/7616
Upstream sequence
ggaaaaaatcaaactatctctctgtgccaacaatatgtttctattcctagaaaactttaaagacttcgccaaagactccccgaactgataaatcaattca
Downstream sequence
gtgtggtggtcagatgcattggctttggtgtcagaatctaacactagcttgtggactttggcaggtcactaatttcttagggcctcagatttttcatcca
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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