VISDB Viral Integration Site DataBase

VIS ID

TVIS10001613

Fusion event

HBV-chr12 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr12

Cytoband

q13.3

Reference genome

Start

End

57979584/57585801 (Hg38)

Location type

Promoter;downstream

Target gene

KIF5A ; PIP4K2C

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-125b-5p ; hsa-mir-101-5p ; hsa-mir-142-5p ; hsa-mir-374a-3p ; hsa-mir-340-5p ; hsa-mir-545-3p ; hsa-mir-921 ; hsa-mir-3174 ; hsa-mir-3617-3p ; hsa-mir-548at-5p ; hsa-mir-5590-5p ; hsa-mir-5590-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-6828-5p ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-4758-5p ; hsa-mir-1238-5p ; hsa-mir-526b-5p ; hsa-mir-3659 ; hsa-mir-574-5p ; hsa-mir-20b-3p ; hsa-mir-3137 ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-6081 ; hsa-mir-4722-5p ; hsa-mir-3605-5p ; hsa-mir-4459 ; hsa-mir-7852-3p ; hsa-mir-6165 ; hsa-mir-1265 ; hsa-mir-361-5p ; hsa-mir-561-3p ; hsa-mir-7977 ; hsa-mir-6849-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-1185-5p ; hsa-mir-3190-3p ; hsa-mir-3679-5p ; hsa-mir-451b ; hsa-mir-4525 ; hsa-mir-4534 ; hsa-mir-4668-5p ; hsa-mir-4716-3p ; hsa-mir-4796-3p ; hsa-mir-4802-5p ; hsa-mir-5010-5p ; hsa-mir-548az-5p ; hsa-mir-548t-5p ; hsa-mir-6079 ; hsa-mir-671-5p ; hsa-mir-6794-5p ; hsa-mir-6894-5p ; hsa-mir-7109-3p ; hsa-mir-7154-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-8082 ; hsa-mir-1324 ; hsa-mir-140-3p ; hsa-mir-188-3p ; hsa-mir-3120-3p ; hsa-mir-3667-3p ; hsa-mir-3914 ; hsa-mir-5000-5p ; hsa-mir-6729-3p ; hsa-mir-6868-3p ; hsa-mir-873-5p

Nearest miRNA

hsa-mir-1228/Upstream/66542; hsa-let-7i/Downstream/162817;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/35658, chr12-CpG: 56/Downstream/5192

Upstream sequence

GCTGCACTGGCCCATGACTCCTTCAAGGAAAAGAGGCCCTGCTCCCTTTACCTGCTGAGCTCCTTTTAGCAGTTAGGGAGAACTGCAGGGGGAAAAATAC

Downstream sequence

CAGTGGAGTGTGGAATAAATCCAAAGCAGTGATTTTTAAATGTTTTTCAAAAACAAATCTTACATAGAACCCCAATATAAAAAATAAAGTAATGCAGACC