NUB1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001618
Fusion event
HBV-NUB1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
151075013/151377927 (Hg38)
End
151075013/151377927 (Hg38)
Location type
UTR3
Fragile sites / regions
FRA7I
Target gene
NUB1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-183-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-10399/Upstream/139389; hsa-mir-153-2/Downstream/55562;
Nearest TSS
ENST00000635602/Upstream/9097; ENST00000465549/Downstream/17990;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/35877, chr7-CpG: 108/Downstream/3449
Upstream sequence
AGGGCCTTGAATCTTGTAGGCCATAATCCACATTATAGTAATTGTCAAGGGTTTGTTTTTTCCCATCCGcccccccccccccccccccccccccccccAC
Downstream sequence
GGGAAAGGTTTAAATGCTAACCAAAGCaatttatttttaattaatatttttaGACTCTGTGCTGTCATACTGAACTCACTGCTAGCTAAGAGACCTATCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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