Basic Information
VIS ID
TVIS10001619
Fusion event
HBV-MIR5684 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
165534792/164613640 (Hg38)
End
165534792/164613640 (Hg38)
Location type
ncRNA_intronic
Target gene
MIR5684
Nearest miRNA
hsa-mir-12113/Upstream/1520012; hsa-mir-1305/Downstream/772602;
Nearest TSS
ENST00000502981/Upstream/229590; ENST00000515485/Downstream/140424;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/229615, chr4-CpG: 38/Downstream/343244
Upstream sequence
AATTAGGACCTAAATCTATAATATAAACTTCTTGGATGCCAGTCTTACTCATAGCTGACACATTTTAGATCCTACTGGAAAACTAAGAAATGCCTCTTAT
Downstream sequence
ACTGAAAAAAAAATTCTTTTACATTGCTTTCCTTGGCACTTCTACAGATACAACTCTTTCCTTTTCAATAGTTAGAAAAAGGTCAGTTCTTCAAATCTGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate