Basic Information
VIS ID
TVIS10001627
Fusion event
HBV-chr19 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1707132/1707133 (Hg38)
End
1707132/1707133 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-1302-11/Upstream/893480; hsa-let-7e/Downstream/109026;
Nearest TSS
ENST00000633603/Upstream/54528; ENST00000586506/Downstream/40923;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/7879, chr19-CpG: 35/Downstream/11670
Nearby gene
TCF3(-54804) ; ONECUT3(+46530) ;
Nearest cancer related gene
TCF3(OG, -54804) ;
Upstream sequence
tgggaggctgaggcagaagaatcacttgcacctgggaggcggaggttgcagtgagccgagattgcgccattgcactccatcctgggtgacagagcaagac
Downstream sequence
tctgtctcaaaaaaaaaaaaagaaagaaagaaagaaaaGAAAAGAAAAGCAGAGGCGGGTACAGTTGGACAACCCACACTCACTCCCGCCTTGGTGTCCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate