Basic Information
VIS ID
TVIS10001639
Fusion event
HBV-SYNDIG1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
24559069/24578433 (Hg38)
End
24559069/24578433 (Hg38)
Location type
Intronic
Target gene
SYNDIG1
miRNAs that regulate target gene
hsa-mir-17-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/6107742; hsa-mir-1-1/Downstream/1629753;
Nearest TSS
ENST00000382410/Upstream/76088; ENST00000482637/Downstream/6469;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/107032, chr20-CpG: 18/Downstream/339885
Upstream sequence
tccagaggctgaggcaggagaattgcttgaacccgggaggcggaggttgcagcgagccccaatcgcgccactgcactccagctgggagacagtgcgagac
Downstream sequence
tctgtatcaaaaaaaaaaaaaagaaagaaagaaaaagaaaagaaaaaaaaaggaagagagtcagaaagtagacaaatcggtatcacgtgaatgcagagaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate