Basic Information
VIS ID
TVIS10001648
Fusion event
HBV-PLPP1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
54808290/55512462 (Hg38)
End
54808290/55512462 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5H
Target gene
PLPP1
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-26b-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-mir-10397/Upstream/3536; hsa-mir-103a-1/Downstream/3017581;
Nearest TSS
ENST00000502646/Upstream/44172; ENST00000506848/Downstream/22489;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/204386, chr5-CpG: 23/Downstream/18320
Upstream sequence
atatacgtatatacgtatatacatttatatatatacgtatatacgtatatacatgtatatacgtatatacgtatatacatgtatatacgtatatacgtat
Downstream sequence
tgtctcaaaaaaaaaaaaaaagaaagaaagaaagaaaagaaaagaaaagaaaagaaagaaagaaagaaagaaagaaagaaagaaagaaagaaagaaagaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate