Basic Information
VIS ID
TVIS10001652
Fusion event
HBV-chr8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
70951130/70038895 (Hg38)
End
70951130/70038895 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/5659638; hsa-mir-10400/Downstream/4509648;
Nearest TSS
ENST00000518652/Upstream/195596; ENST00000520259/Downstream/32432;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/3831, chr8-CpG: 262/Downstream/30743
Nearby gene
SLCO5A1(-203831) ; PRDM14(+12756) ;
Nearest cancer related gene
PRDM14(OG, +12756) ;
Upstream sequence
gcaagctccgcctcccggattcacaccattctcctgcttcagcctcctgactagctgggactacaggcacccgccacctcgcctggctaattttttgtat
Downstream sequence
ttttgaaaagatgcctctagctgggaagaaaatgatctggattggggcaagaacagatataaaagttattttatcagatgggttgagatgagggccttag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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