VISDB Viral Integration Site DataBase

VIS ID

TVIS10001659

Fusion event

HBV-BTRC integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr10

Cytoband

q24.32

Reference genome

Start

End

103178795/101419038 (Hg38)

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-183-5p ; hsa-mir-10a-5p ; hsa-mir-193b-3p ; hsa-mir-320a ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-let-7e-5p ; hsa-mir-195-5p ; hsa-mir-497-5p ; hsa-mir-4271 ; hsa-mir-548au-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-3974 ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-7155-3p ; hsa-mir-3136-3p ; hsa-mir-4722-5p ; hsa-mir-5008-5p ; hsa-mir-605-3p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-4762-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-554 ; hsa-mir-4709-5p ; hsa-mir-624-5p ; hsa-mir-101-3p ; hsa-mir-6884-5p ; hsa-mir-421 ; hsa-mir-3115 ; hsa-mir-505-3p ; hsa-mir-493-3p ; hsa-mir-6871-5p ; hsa-mir-15b-5p ; hsa-mir-10a-3p

Nearest miRNA

hsa-mir-107/Upstream/443954; hsa-mir-1307/Downstream/182379;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/64381, chr10-CpG: 53/Downstream/147381

Upstream sequence

ctcaatcaagctaattaacatatctgtaacctagcatacATGTAACATCTCACAGTTTCTtttctttctttctttcttttttttttttttgatacagagt

Downstream sequence

ctcgctctgtcacccaggctggagtgcagtggcacgatcttggctcactgcaacctctgcctcccaggttctggcaattctcctgcctcagcctctggag